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Warning Flea & Tick product (Bravecto)

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Warning Flea & Tick product (Bravecto)

Post by perro dulce on Fri Mar 04, 2016 12:21 pm

(Translated to Spanish below)

Please share this with your friends. We hope by sharing, others will not suffer.

Bravecto is a three month oral flea & tick treatment for dogs. The manufacturer has plans to market a version for cats.

We know firsthand about Bravecto's adverse effects. One dog lost, yet another being observed. We are not out of danger yet.

We were forced to euthanize our beautiful feisty girl (dog), who loved life. She was only 22 month old. She experienced complete kidney failure. Outward symptoms of Chronic kidney failure, are not immediate and can take months to manifest. That time gap between dosing and symptoms is not unusual. Many will not make that connection to their dog's illness/death due to Bravecto. Our family, sweet girl, and our wonderful Lake Chapala veterinarian team, put up a fierce fight which included IV fluids, to supply nutrients and dialysis. I doubt that type of fight would have been as personalized, complete/compassionate, or affordable in the US. She was definitely not just another pet to that vet team. Blood workup on our other dog, her litter mate, showed elevated BUN levels. Our third dog has experienced lack of appetite and nausea.

Autopsy results indicated Chronic Kidney Failure. This finding ruled out congenital and acute Kidney Disease. Autopsy ruled out a poison being recently digested. The veterinarian stated that her kidneys were damaged due to a lymphoplasmacytic reaction, due to the presence of something the dog was introduced to orally. The immune system then attacked that substance relentlessly. This resulted in kidney damage over the course of weeks-months. Our other dog showed elevated levels in his blood work up. Due to that elevated BUN, our veterinarian stated this was something both dogs were introduced to orally.

We have filed reports. We feel we must notify other dog guardians. This product is sold internationally. Since Bravecto by Merck, was approved in the U.S. in 2014, a total of 5,319 ADE reports have been filed with the FDA (through January 6, 2016) including 160 reported deaths. These numbers only include ADE reports filed in the U.S. I recently found out, there is a new report due to be released. The "Does Bravecto Kill Dogs" FB group, offers the latest reports and data as it becomes available. Upon viewing the autopsy. Dr. Fox stated: I think the autopsy findings do indicate acute nephritis---white cell infiltration blicking normal kidney function. The vet should file the report with Bravecto's manufacturer and local distributor.

Dr. Michael W. Fox will be doing a column with information on Bravecto risks, which should appear in the Washington Post Mid March/2016.

May other dogs be spared to enjoy life, bark, play and cuddle, as a result of this information we are sharing.


Links to the FDA adverse event reports, the Facebook group and the EMA/CVMP summary of opinion:

http://yourpetsneedthis.com/wp-content/uploads/2015/11/Bravecto-fluralaner-ADE-report.pdf

and

https://www.facebook.com/groups/411371212394679/

and

http://www.ema.europa.eu/docs/en_GB/document_library/Summary_of_opinion/veterinary/002526/WC500198749.pdf

Cumulative effects from repeated exposure to carcinogenic chemical pesticides, may take years to surface in your loved pet. Take a moment and visit the FB Bravecto support group. Then make an educated decision.

SPANISH:

Por favor comparte esto con tus amigos. Esperamos que al compartir, otros no vayan a sufrir.
Bravecto es un tratamiento de pulgas y garrapatas por vía oral durante tres meses para los perros. El fabricante tiene planes para comercializar una versión para gatos.

Sabemos de primera mano sobre los efectos adversos de Bravecto. Un perro perdido, otro siendo observado. No estamos fuera de peligro todavía.
Nos vimos obligados a practicar la eutanasia a nuestra hermosa chica luchadora (perra), que amaba la vida. Ella tenía sólo 22 meses de edad.
Experimentó una insuficiencia renal completa. Los síntomas externos de la insuficiencia renal crónica, no son inmediatos y pueden tardar meses en manifestarse. Ese espacio de tiempo entre la dosificación y los síntomas no es inusual. Muchos no harán la conexión entre la enfermedad de su perro y la muerte debido a Bravecto.

Nuestra familia, esa chica dulce,y nuestro maravilloso equipo veterinario del Lago de Chapala, realizaron una feroz lucha que incluía líquidos por vía intravenosa para suministrar nutrientes y diálisis. Dudo que tipo de lucha hubiese sido lo más personalizada, completa, compasiva y asequible en los EE.UU.
Ella definitivamente no una mascota más para que el equipo veterinario. Un análisis de sangre en nuestro otro perro, su compañero de camada, mostró niveles de BUN elevadas. Nuestro tercer perro ha experimentado falta de apetito y náuseas.
Resultados de la autopsia indican insuficiencia renal crónica. Este hallazgo descarta la enfermedad renal congénita y aguda. La autopsia descarta un veneno recentemiente digerido.

El veterinario dijo que sus riñones fueron dañados debido a una reacción linfoplasmocítica, debido a la presencia de algo que el perro se introdujo en forma oral. El sistema inmunitario ataca la sustancia sin descanso. Esto dio como resultado el daño renal en el curso de semanas, meses.
Nuestro otro perro mostró niveles elevados en su sangre. Debido a que el BUN es elevado, nuestro veterinario indicó que esto era algo producto de algo que les fue introducidos a los perros por vía oral.

Hemos presentado informes. Sentimos que debemos notificar a los demás guardianes de perros. Este producto se vende a nivel internacional.Desde que Bravecto de Merck, fue aprobado en los EE.UU. en 2014, un total de 5.319 informes de ADE se han presentado ante la FDA (hasta el 6 de enero de, 2016) incluyendo 160 muertes.

Estas cifras sólo incluyen los informes ADE presentadas en los EE.UU. Recientemente descubrí, que hay un nuevo informe que se publicará. El grupo FB "Dont Kill Dogs with Bravecto", ofrece los últimos informes y datos disponibles desde la óptica de la autopsia. El Dr. Fox declaró: Creo que los resultados de la autopsia no indican la nefritis aguda --- la infiltración de glóbulos blancos bloquean la función renal normal. El veterinario debe presentar el informe con el fabricante del Bravecto y su distribuidor local.

El Dr. Michael W. Fox va a hacer una columna con información sobre los riesgos de Bravecto que deberá aparecer en el Washington Post a mediados de marzo / 2016.

Al difundir podemos otorgar a otros perros la posibilidad de disfrutar de la vida, del juego, retozar y del abrazo, como resultado de esta información que estamos compartiendo.

Los enlaces a los informes de eventos adversos de la FDA, del grupo de Facebook y el resumen de la opinión de EMA / CVMP:


http://yourpetsneedthis.com/wp-content/uploads/2015/11/Bravecto-fluralaner-ADE-report.pdf

y

https://www.facebook.com/groups/411371212394679/

y

http://www.ema.europa.eu/docs/en_GB/document_library/Summary_of_opinion/veterinary/002526/WC500198749.pdf

Los efectos acumulativos de la exposición repetida a los pesticidas químicos cancerígenos, pueden tardar años en salir a la superficie en su mascotaamada. Tome un momento y visite el grupo de apoyo de FB Bravecto y tome una decisión informada.

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Re: Warning Flea & Tick product (Bravecto)

Post by kipissippi on Fri Mar 04, 2016 1:41 pm

Damn.  I gave all of my fur kids Bravecto last week!  I've tried so many things and the fleas just weren't impressed.  This worked... I'm so hoping that it's only the fleas it kills.
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Re: Warning Flea & Tick product (Bravecto)

Post by Flamingo on Fri Mar 04, 2016 3:35 pm

Take a deep breath. MANY MANY dogs have been taking Bravecto with no adverse affects. This warning appears to be from a few disgruntled individuals rather than an actual problem. This has been checked by Snopes and is considered UNPROVEN. Now, go worry about something else.

http://www.snopes.com/bravecto-flea-and-tick-warning/
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Re: Warning Flea & Tick product (Bravecto)

Post by perro dulce on Fri Mar 04, 2016 10:05 pm

It is unfortunate that people are quoting Snopes, on this subject of Bravecto.

Vet, Michael Mogavero DVM, SELLS Bravecto,and is quoted as the main source of debunking Bravecto risks. Vet Michael Mogavero, speaks highly of both Bravecto's and Merck, This is who Snopes quotes, to debunk claims regarding dog death and illness. Shame on Snopes for a misleading article. Both sources (snopes and Mogavero) ignore the FDA ADE report, which documents a total of 5,319 ADE reports have been filed with the FDA (through January 6, 2016) including 160 reported deaths. I wonder what Snopes connection is with this serving as a sounding board for a DVM who is connected with Merck, and sells Merck's product.

A vet who sells Bravecto, Michael Mogavero, states that the pharmaceutical company (Merck) will advise us if they have concerns about their product.

Cumulative effects from repeated exposure to carcinogenic chemical pesticides, may take years to surface in your loved pet. Take a moment and visit the FB Bravecto support group. Then make an educated decision.


And we (among others) have a dead dog.



Flamingo wrote:Take a deep breath. MANY MANY dogs have been taking Bravecto with no adverse affects. This warning appears to be from a few disgruntled individuals rather than an actual problem. This has been checked by Snopes and is considered UNPROVEN. Now, go worry about something else.

http://www.snopes.com/bravecto-flea-and-tick-warning/

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Re: Warning Flea & Tick product (Bravecto)

Post by perro dulce on Fri Mar 04, 2016 10:06 pm

I sent you a PM.


kipissippi wrote:Damn.  I gave all of my fur kids Bravecto last week!  I've tried so many things and the fleas just weren't impressed.  This worked... I'm so hoping that it's only the fleas it kills.

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Re: Warning Flea & Tick product (Bravecto)

Post by Zedinmexico on Sat Mar 05, 2016 7:30 am

Advantage seems to work for my four cats. Not effective for some folks cats??


Thanks for the info on Bravecto. Hmmmmm

Z


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Re: Warning Flea & Tick product (Bravecto)

Post by perro dulce on Sat Mar 05, 2016 7:50 am

You're welcome.

Hopefully a few dogs, which may have responded unfavorably will be spared, in sharing our story.



Zedinmexico wrote:Advantage seems to work for my four cats.  Not effective for  some folks cats??


Thanks for the info on Bravecto.  Hmmmmm

Z


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Re: Warning Flea & Tick product (Bravecto)

Post by Flamingo on Mon Mar 07, 2016 4:17 pm

I decided to answer this post with a story of my own. I am quite allergic to several medicines and have bad side-affects. Does this mean no one else should take these medicines, even though they have helped thousands of people? Of course not. It means I need to remember the names of the medicines and not take them again.

Unfortunately a few dogs with compromising health issues had bad reactions to a product and died. This is very sad, but it does not mean that no one should consider using the product.
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Re: Warning Flea & Tick product (Bravecto)

Post by perro dulce on Mon Mar 07, 2016 8:35 pm

Three of my dogs affected. All exceptionally well cared for since conception.  Their mothers in excellent condition.

Two young healthy (2 year olds)  dogs affected. One dead. One elevated BUN.
But I am repeating myself.  View my thorough post above.
One 4 year old fighting nausea.

It is not an allergy these dogs experienced.  You cannot equate this to an allergic reaction.
No compromising preexisting health issues whatsoever.
In fact many of the dogs were exceptionally young and healthy.
Not a few dogs.
Many had prior illness or congenital issues ruled out with expensive autopsies.  
Vet said that my dog which died, was athletic and in superior health, but for the autopsy finding of
Chronic Kidney failure. I repeat: It was not congenital (since birth). It was not a pre-existing health condition.

I don't know where you are going with this, but it is not just my dogs which were hurt by this.  See the ADE report of over 5,000 cases and many a death.  Yes, I have one dead dog.  Sadly, She is not alone.  

Latest data coming out now from Europe / USA is the connection to birth defects and litter deaths, when given to pregnant dogs.

I wish it were a fluke, and I was alone (or one of just few) in the premature death of my dog.

In her and our time of crisis, I have a responsibility, to inform others so that they are aware.



Flamingo wrote:I decided to answer this post with a story of my own. I am quite allergic to several medicines and have bad side-affects. Does this mean no one else should take these medicines, even though they have helped thousands of people? Of course not. It means I need to remember the names of the medicines and not take them again.

Unfortunately a few dogs with compromising health issues had bad reactions to a product and died. This is very sad, but it does not mean that no one should consider using the product.

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Re: Warning Flea & Tick product (Bravecto)

Post by itsme on Tue Mar 08, 2016 7:36 am

Boy, sounds as if Flamingo has an interest in that company, else why so cavalier about dogs dying?

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Re: Warning Flea & Tick product (Bravecto)

Post by Trailrunner on Tue Mar 08, 2016 8:11 am

Yes, Perro Dulce, I am very sorry for your loss and will steer clear of this product just in case. . . I was once offered this product by 2 local vets but decided against it as I hadn't heard of it and was a bit leery. Luckily, Advantage works well for us.

Your experience is not to be diminished.
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Re: Warning Flea & Tick product (Bravecto)

Post by Lucky Girl on Tue Mar 08, 2016 8:57 am

Perro Dulce, so sorry for your loss.
Thank you for the warning, I have used the product 3x on our dog, no side effects so far, but I will no longer use it. The very possibility of something happening because I ignored a warning would haunt me.

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Re: Warning Flea & Tick product (Bravecto)

Post by perro dulce on Wed Mar 09, 2016 9:03 am

Thank you, for your kind and considerate words.

Trailrunner wrote:Yes, Perro Dulce, I am very sorry for your loss and will steer clear of this product just in case. . .  I was once offered this product by 2 local vets but decided against it as I hadn't heard of it and was a bit leery.  Luckily, Advantage works well for us.

Your experience is not to be diminished.

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Re: Warning Flea & Tick product (Bravecto)

Post by perro dulce on Wed Mar 09, 2016 9:08 am

You are welcome, and thank you for your condolences and thoughts.
It is a comfort to know that some good may come of this.


Lucky Girl wrote:Perro Dulce, so sorry for your loss.
Thank you for the warning, I have used the product  3x on our dog, no side effects so far, but I will no longer use it. The very possibility of something happening because I ignored a warning would haunt me.

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Re: Warning Flea & Tick product (Bravecto)

Post by Flamingo on Thu Mar 10, 2016 11:27 am

From everything I have read, as with any strong medication, there may be side effects. But the Facebook page seems to be the only place with dire warnings.

Here is what I found that seems to be a balanced view.
http://www.veterinaryplace.com/dog-medicine/bravecto/

Decide for yourself but I remain spectacle.
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